Pilot Plant Network

Addressing Infrastructure Gaps to Build the Biomanufacturing Industry

The United States faces a foundational gap in domestic pilot- and intermediate-scale bioindustrial manufacturing infrastructure. As a result, American companies often must seek relevant facilities overseas to scale-up their manufacturing for innovative bio-based products from the laboratory to commercial production.   

To address this, BioMADE launched its plan for a network of pilot-scale bioindustrial manufacturing facilities around the United States in 2023. With federal and state co-investments, the BioMADE Pilot Plant Network (PPN) will grow to include facilities throughout the U.S. that provide an essential service to growing bioindustrial manufacturing businesses.

These facilities will:

  • Benefit start-ups, industry, and U.S. Government customers alike

  • Support American farmers and provide new markets for their feedstocks

  • Re-shore manufacturing jobs and retain American R&D efforts

  • Create varied and far-reaching career pathways

  • Build a domestic supply chain for everyday and valuable products used by Americans

  • Reduce reliance on foreign petroleum and other inputs

  • Build and preserve U.S. leadership in the 21st century bioeconomy

Sites are currently announced in Minnesota, California, and Iowa. BioMADE continues to seek partnership opportunities to expand the network in additional states. If your state is interested in partnership, reach out to infrastructure@biomade.org to start a conversation.


  • Minnesota

    Pilot- and demonstration- scale facility with 5,000- and 25,000-liter fermenters and explosion-proof capabilities.

  • Iowa

    Pilot-scale facility with 1,000- and 10,000-liter fermenters, spray drying, and food-grade capabilities.

  • California

    Pilot-scale facility with 4,000-liter fermenters, spray drying, and food-grade capabilities.

Move from the benchtop toward commercial-scale production

Take your products out of the lab and toward commercial production at BioMADE’s Pilot Plant Network! Scale faster and more efficiently with the expertise and unrivaled network found at BioMADE’s piloting facilities.

BioMADE’s multi-user facilities provide companies of all sizes access to state-of-the-art industrial fermentation equipment and downstream processing services, all managed by world-class operational experts. Accelerate your company’s innovative products and technologies right here in the U.S. without the burden of raising significant capital of your own.

BioMADE’s Pilot Plant Network will serve customers from small-scale development capabilities to commercial testing and process refinement.